Spontaneous "Second Wind" and Glucose-Induced Second "Second Wind" in McArdle Disease

Spontaneous "second wind" and glucose-induced second "second wind" in McArdle disease: oxidative mechanisms.

BACKGROUND Blocked glycogen breakdown in McArdle disease impairs oxidative as well as anaerobic metabolism, but the contribution of impaired oxidative phosphorylation to everyday symptoms of McArdle disease remains poorly defined. OBJECTIVE To evaluate the oxidative implications of the spontaneous second wind and variables that influence the development of this typical feature of McArdle dise...

From exercise intolerance to functional improvement: the second wind phenomenon in the identification of McArdle disease.

McArdle disease is the most common of the glycogen storage diseases. Onset of symptoms is usually in childhood with muscle pain and restricted exercise capacity. Signs and symptoms are often ignored in children or put down to 'growing pains' and thus diagnosis is often delayed. Misdiagnosis is not uncommon because several other conditions such as muscular dystrophy and muscle channelopathies ca...

Second Wind Phenomenon in Chronic Coronary Heart Disease.

Electrostatic Fluid Accelerator and Air Purifier – The Second Wind

Transformation of ionic pump (electron wind, Electrostatic Fluid Accelerator) technology from curious laboratory experiments to practical industrially acceptable devices requires pushing the basic technology to its physical limits. This paper presents a description of main design optimization options. A numerical modeling study demonstrates the effect of geometry and voltage distribution on the...

First effort angina; second wind in angina pectoris.